Table 2.
Baseline characteristics of patients without a history of atrial fibrillation at enrolment, stratified by presence or absence of incident atrial fibrillation after enrolment
| Variable | No incident AF (N=7331) |
Incident AF (N=244) |
P value |
| Demographics and clinical variables | |||
| Female | 1743 (23.8) | 69 (28.3) | 0.10 |
| Age (years) | 66.8 (8.6) | 66.3 (8.8) | 0.43 |
| BMI (kg/m2) | 27.5 (4.7) | 28.5 (4.8) | 0.001 |
| SBP (mm Hg) | 131.5 (17.7) | 133.5 (18.1) | 0.09 |
| Heart rate (bpm) | 68.2 (10.7) | 67.7 (11.5) | 0.48 |
| Smoking status | |||
| Never | 2731 (37.3) | 90 (36.9) | 0.56 |
| Former | 3589 (49.0) | 115 (47.1) | |
| Current | 1010 (13.8) | 39 (16.0) | |
| Living alone | 1034 (14.3) | 28 (11.5) | 0.23 |
| Region | <0.001 | ||
| Europe | 3532 (48.2) | 188 (77.1) | |
| Asia and Australia | 1935 (26.4) | 7 (2.9) | |
| Latin America | 1027 (14.0) | 32 (13.1) | |
| North America | 837 (11.4) | 17 (7.0) | |
| Comorbidities and medical history | |||
| Diabetes mellitus | 0.80 | ||
| No diabetes | 4875 (67.0) | 164 (67.8) | |
| Non–insulin-treated | 1724 (23.7) | 56 (23.1) | |
| Insulin-treated | 681 (9.4) | 22 (9.1) | |
| Second prior MI | 739 (10.1) | 33 (13.5) | 0.08 |
| Chronic kidney disease | 535 (7.3) | 28 (11.5) | 0.01 |
| Major bleeding | 182 (2.5) | 7 (2.9) | 0.70 |
| Peripheral arterial disease | 474 (6.5) | 19 (7.8) | 0.08 |
| Congestive heart failure | 748 (10.2) | 39 (16.0) | 0.004 |
| Angina | 709 (9.7) | 54 (22.1) | <0.0001 |
| Valve replacement/repair | 58 (0.8) | 2 (0.8) | 0.96 |
| Stroke or transient ischaemic attack | 387 (5.3) | 12 (4.9) | 0.80 |
| Cancer | 505 (6.9) | 17 (7.0) | 0.96 |
| COPD | 494 (6.7) | 27 (11.1) | 0.009 |
| CV event requiring hospital stay in the past 6 months | 313 (4.3) | 20 (8.2) | 0.003 |
| Bleeding event requiring hospital stay in the past 6 months | 42 (0.6) | 3 (1.2) | 0.19 |
| Cardiac surgery in the past 6 months | 28 (0.4) | 4 (1.6) | 0.003 |
| Visit to the cardiologist in the past 6 months | 2324 (31.7) | 83 (34.0) | 0.44 |
| ED visit in the past 6 months for bleeding or CV disease | 384 (5.2) | 31 (12.7) | <0.0001 |
| GP visit in the past 6 months for bleeding or CV disease | 1467 (20.0) | 59 (24.2) | 0.11 |
| Details of index event | |||
| Type of index MI | 0.47 | ||
| STEMI | 3724 (50.8) | 121 (49.6) | |
| NSTEMI | 3125 (42.6) | 111 (45.5) | |
| Unknown | 482 (6.6) | 12 (4.9) | |
| Management of index MI | 0.06 | ||
| PCI | 5977 (81.5) | 185 (75.8) | |
| CABG | 543 (7.4) | 21 (8.6) | |
| Medical | 811 (11.1) | 38 (15.6) | |
Continuous variables presented as mean (%).
AF, atrial fibrillation; BMI, body mass index; CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; CV, cardiovascular; ED, emergency department; GP, general practitioner; MI, myocardial infarction; NSTEMI, non-ST elevation myocardial infarction; PCI, percutaneous coronary intervention; SBP, systolic blood pressure; STEMI, ST elevation myocardial infarction.