Table 3.
Summary of TEAEs
| TEAE by preferred term* | All patients n (%) (N = 49) | |
|---|---|---|
| Any grade | Grade ≥3 | |
| Any TEAE | 49 (100) | 45 (92) |
| Nonhematologic TEAEs | ||
| Diarrhea | 32 (65) | 5 (10) |
| Fatigue | 23 (47) | 3 (6) |
| Nausea | 23 (47) | 2 (4) |
| Upper respiratory tract infection | 19 (39) | 0 |
| Dyspnea | 17 (35) | 3 (6) |
| Insomnia | 17 (35) | 5 (10) |
| Cough | 16 (33) | 0 |
| Vomiting | 14 (29) | 3 (6) |
| Hypertension | 13 (27) | 8 (16) |
| Dyspepsia | 12 (24) | 0 |
| Edema peripheral | 12 (24) | 0 |
| Headache | 10 (20) | 0 |
| Hypocalcemia | 10 (20) | 0 |
| Hypokalemia | 10 (20) | 1 (2) |
| Sinusitis | 10 (20) | 0 |
| Abdominal pain | 9 (18) | 0 |
| Hypophosphatemia | 9 (18) | 5 (10) |
| Pneumonia | 9 (18) | 6 (12) |
| Hyperglycemia | 8 (16) | 3 (6) |
| Hypomagnesemia | 8 (16) | 0 |
| Influenza | 8 (16) | 3 (6) |
| Hematologic TEAEs | ||
| Lymphopenia† | 17 (35) | 15 (31) |
| Thrombocytopenia‡ | 15 (31) | 4 (8) |
| Neutropenia§ | 11 (22) | 6 (12) |
| Leukopenia|| | 11 (22) | 6 (12) |
| Anemia | 9 (18) | 4 (8) |
*
TEAEs presented are those occurring in ≥15% of patients for any grade or in ≥10% of patients for grades 3 and 4.
†
Includes decreased lymphocyte count.
‡
Includes decreased platelet count.
§
Includes decreased neutrophil count.
||Includes decreased white blood cell count.