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. 2021 Dec 3;12:775151. doi: 10.3389/fimmu.2021.775151

Figure 6.

Figure 6

RDO24 mAb docks on the PSI domain of MET. A three-dimensional model of RDO24 variable fragment (Fv) was generated by Rosetta homology modeling. The complementarity determining regions (CDR) of the VH and VL domains are represented in colors. The framework regions of the VH and VL are shown in dark and light grey, respectively. The CDR sequences of RDO24 are represented according to the Clothia numbering scheme (A). RDO24 was docked to MET (PDB accession: 1SHY) using the ZDOCK docking program. The figures were drawn with Discovery Studio Visualizer. The CDR of the VH and VL domains are shown in colors. The SEMA domain is shown in light pink, the PSI domain in yellow and HGF in green (B); enlarged view in (C).