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. 2021 Oct 28;186(1):53–64. doi: 10.1530/EJE-21-0669

Table 3.

Within-group changes in metabolic syndrome and metabolic parameters from baseline to 12 months. Differences were tested with multilevel logistic regression analyses for categorical variables and with multilevel linear regression analyses for continuous variables, combined with a bootstrap procedure in case of a non-normal distribution.

Group At baseline At 3 months At 6 months At 9 months At 12 months Change P value within
Metabolic syndrome (%)
  SMS+ 41.9 32.4 28.9 26.8 25.3 −16.5 0.190
  SMS− 49.8 37.6 32.9 30.2 28.2 −21.6 0.037
  CAU 37.9 41.6 43.1 44.1 44.8 7.0 0.509
Metabolic parameters
 cMetS z-score
  SMS+ 0.44 0.20 0.11 0.06 0.02 −0.42 0.002
  SMS− 0.41 0.19 0.16 0.17 0.20 −0.21 0.027
  CAU 0.39 0.22 0.23 0.28 0.36 −0.03 0.733
 HOMA-IR
  SMS+ 3.33 3.12 3.04 2.99 2.95 −0.38 0.329
  SMS− 3.79 3.70 3.67 3.65 3.63 −0.15 0.658
  CAU 3.87 3.81 3.79 3.78 3.76 −0.11 0.842
 SBP (mmHg)
  SMS+ 120 117 116 115 115 −5 0.053
  SMS− 121 119 117 117 116 −5 0.010
  CAU 119 120 120 120 121 1 0.450
 DBP (mmHg)
  SMS+ 78 76 75 75 74 −4 0.034
  SMS− 79 77 77 76 76 −3 0.040
  CAU 78 78 78 78 78 0 0.821
 Waist (cm)
  SMS+ 102.9 98.4 96.5 95.4 94.5 −8.4 0.013
  SMS− 100.1 98.1 97.2 96.7 96.3 −3.7 0.097
  CAU 100.3 97.6 96.5 95.8 95.2 −5.1 0.016
 Glucose (mmol/L)
  SMS+ 5.1 5.0 5.0 5.0 5.0 −0.2 0.150
  SMS− 5.2 5.1 5.1 5.1 5.1 −0.1 0.371
  CAU 5.0 5.1 5.1 5.1 5.2 0.1 0.375
 Insulin (pmol/L)
  SMS+ 100 94 92 90 89 −11 0.376
  SMS− 111 110 110 110 110 −2 0.842
  CAU 118 114 113 112 111 −8 0.700
 Cholesterol (mmol/L)
  SMS+ 4.7 4.5 4.4 4.4 4.3 −0.4 0.009
  SMS− 4.8 4.7 4.7 4.6 4.6 −0.2 0.092
  CAU 4.7 4.7 4.7 4.7 4.7 0.0 0.836
 HDL (mmol/L)
  SMS+ 0.94 0.92 0.91 0.90 0.90 −0.04 0.200
  SMS− 0.95 0.96 0.96 0.96 0.97 0.02 0.643
  CAU 0.87 0.90 0.92 0.92 0.93 0.06 0.022
 LDL (mmol/L)
  SMS+ 3.21 3.05 2.99 2.94 2.91 −0.29 0.027
  SMS− 3.24 3.15 3.11 3.09 3.07 −0.17 0.115
  CAU 3.25 3.19 3.16 3.15 3.14 −0.11 0.281
 TG (mmol/L)
  SMS+ 1.33 1.27 1.25 1.23 1.22 −0.11 0.441
  SMS− 1.39 1.31 1.28 1.26 1.24 −0.15 0.065
  CAU 1.39 1.42 1.43 1.44 1.45 0.06 0.593

CAU, care as usual; cMetS z-score, continuous metabolic syndrome Z score; DBP, diastolic blood pressure; HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment for insulin resistance; LDL, low-density lipoprotein; SBP, systolic blood pressure; SMS−, lifestyle intervention without SMS support; SMS+, lifestyle intervention with SMS support; TG, triglyceride.

Statistically significant values (P<0.05) are presented in bold.