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. 2021 Dec 14;9:e12330. doi: 10.7717/peerj.12330

Table 3. Effect of Design on magnitude of CPM effect, adjusted for order effect.

Absolute data Relative data (%)
Design Order Design Order
Location β, 95% CI P-Value f2 β, 95% CI P-value β, 95% CI P-Value f2 β, 95% CI P-Value
Mechanical Cervical spine −3 [−21, 15] .723 0.00 24 [6, 43] .009 −6.1 [−10.1, −2.1] .003 0.10 0.1 [−3.9, 4.1] .967
Pressure Pain Threshold (PPT)a Forearm 5 [−16, 26] .633 0.00 23 [2, 44] .034 −4.5 [−9.0, 0.1] .055 0.04 −0.7 [−5.3, 3.8] .745
Lower leg −5 [−40, 30] .780 0.00 46 [11, 81] .010 −5.9 [−11.7, −0.1] .046 0.05 −0.3 [−5.4, 6.1] .907
Thermal Cervical spine −1 [−5, 2] .501 0.01 3 [−1, 6] .120 −5.1 [−13.4, 3.1] .214 0.03 6.3 [−1.9, 14.5] .129
Heat Test Stimulus (HTS)b Forearm −1 [ −4, 1] .324 0.01 3 [0, 6] .060 −1.7 [−9.8, 6.3] .670 0.00 5.8 [−2.2, 13.9] .156
Lower leg 1 [−2, 3] .579 0.01 5 [2, 7] <.001 −1.9 [−8.6, 4.9] .586 0.00 9.2 [2.4, 15.9] .009

Notes.

Significant effects are printed in bold. Test location at the cervical spine is paraspinal muscles over C5/C6, at the forearm is extensor carpi radialis muscle and at the lower leg is the tibialis anterior muscle. A negative coefficient for design indicates the sequential design is lower compared to the parallel design. Order effect is based upon if the design was either first or second. A negative coefficient for order indicates that the first measurement is lower than the second measurement.

a

Absolute data in kPa.

b

Absolute data in VAS (0–100).