Table 4. Main effect of experiments on magnitude of CPM effect.

		Absolute data				Relative data (%)
		Experiment 1		Experiment 3		Experiment 1		Experiment 3
	Location	β, 95% CI	P-value	β, 95% CI	P-Value	β, 95% CI	P-Value	β, 95% CI	P-Value
Mechanical	Cervical spine	17 [−15, 48]	.296	−21 [−53, 11]	.189	3.5 [−2.9, 9.8]	.282	0.4 [−6.0, 6.7]	.908
Pressure Pain Threshold (PPT)a	Forearm	−19 [−52, 14]	.260	19 [−52; 14]	.252	−3.9 [−10.2, 2.3]	.216	0.1 [−6.2, 6.3]	.984
	Lower leg	47 [−14, 108]	.132	−74 [−135, −13]	.018	5.3 [−2.6, 13.3]	.185	5.2 [−2.8, 13.1]	.197
Thermal	Cervical spine	1 [−2, 5]	.476	–	–	4.6 [−3.9, 13.2]	.284	–	–
Heat Test Stimulus (HTS)b	Forearm	0 [−3, 3]	.773	–	–	3.5 [−4.6, 11.6]	.392	–	–
	Lower leg	−1 [−4, 1]	.321	–	–	−0.1 [−10.1, 10.0]	.987	–	–

Notes.

Significant effects are printed in bold. Test location at the cervical spine is paraspinal muscles over C5/C6, at the forearm is extensor carpi radialis muscle and at the lower leg is the tibialis anterior muscle. Experiment 1; both test stimuli, conditioning stimulus VAS 40/100, Experiment 2 (control); both test stimuli, conditioning stimulus VAS 60/100, Experiment 3; only mechanical test stimulus, conditioning stimulus VAS 60/100. Coefficients shown in comparison with Experiment 2 as control, resulting in the coefficients of Experiment 1 reflecting the difference in the intensity of the conditioning stimulus and the coefficients of Experiment 3 reflecting the difference of single or dual test stimuli. Thermal testing was absent in Experiment 3.

^aAbsolute data in kPa.

^bAbsolute data in VAS (0 –100).