FIG. 5.

Alignment of conserved N termini of Rad30 subfamily DNA polymerases. Sequence alignment of conserved portions of N termini, including motifs I to V of Rad30 proteins from Arabidopsis thaliana (AT), Caenorbabditis elegans (CE), human (HU), Schizosaccharomyces pombe (SP), and S. cerevisiae (SC). Numbers in parenthesis indicate the regions for which amino acid sequences are not shown. Asterisks indicate the highly conserved acidic residues which were individually mutated to alanine in the S. cerevisiae Rad30 protein.