Figure 2:

Effect of individual excipients on measles and rubella vaccine titer after drying. Individual excipients were mixed with monovalent measles or rubella vaccine samples and then dried as films for ~18 h at room temperature (20 – 25°C). All formulations contained 0.8 wt% potassium phosphate buffer (pH 7.5) and 1 wt% CMC. Vaccine titer was normalized to titer of liquid vaccine solutions before drying. The solid lines represent the lower detection limit for each assay (black for measles, grey for rubella). Data are expressed as mean ± standard deviation based on 2 replicates each. No statistical analysis was performed on these data.