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. Author manuscript; available in PMC: 2021 Dec 17.
Published in final edited form as: Nat Cancer. 2021 May 3;2(5):563–574. doi: 10.1038/s43018-021-00197-6

Extended Data Fig. 5 |. Hydrophobicity scores of T-cell contact regions.

Extended Data Fig. 5 |

Hydrophobicity scores were calculated summing the Kyte-Doolittle hydrophobicity score of positions 4 through n-1. The panels are split into all mmps (positive n=119, negative n=2681162), comparison of just those with a anchor in position 2,3 or C-terminus (positive n=55, negative n= 1167363) and those without mutations in position 2,3, or C-terminus (positive n= 64, negative n= 1513799). Box indicates quartiles 2 & 3 and inter quartile range, median indicated by line in box plot, whiskers represent quartile 1 and 4 ± 1.5X IQR or minimum/maximum value if within the whisker values. Significance calculated with Mann-Whitney U test.