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. 2021 Nov 1;117(5):1018–1027. [Article in Portuguese] doi: 10.36660/abc.20190715

Table 2. Characteristics of non-survivors and survivors at 1 year follow-up.

Characteristics Non-survivors
n = 19
Survivors
n = 111
HR (95%CI) p-value
Age (years) 84 (81-87) 83 (80-87) - 0,3
Male sex 36.8% 54.1% - 0,2
BMI (kg/m2) 26.2 (22.6-27.4) 25.2 (22.5-30.1) - 0,8
NYHA FC IV heart failure 57.9% 38.7% - 0,1
Diabetes mellitus 42.1% 36.0% - 0,6
CAD 42.1% 36% - 0,6
PVD 26.3% 23.4% - 0,4
COPD 15.8% 8.1% - 0,3
STS score (%) 17.9 (8.1-30.2) 8.1 (4.7-17.1) 1,03 (1,01-1,06) 0,02
Baseline creatinine (mg/dL) 1.3 (0.8-1.5) 1.1 (0.9-1.3) - 0,8
LVEF (%) 55 (31-73) 64 (50.5-73.0) 0,98 (0,95-1,00) 0,04
Baseline hemoglobin (mg/dL) 11.2 (10.2-12.9) 12.0 (10.6-13.3) - 0,4
Nadir hemoglobin (mg/dL) 8.1 (7.4-9.9) 9.8 (8.4-10.9) 0,68 (0,49-0,94) 0,01
Baseline CRP (mg/dL) 1.5 (0.2-2.8) 0,3 (0,2-0,9) 1,19 (1,06-1,34) <0,0001
Baseline CRP > 0,5 mg/dL 68.8% 29.1% 4,70 (1,63-13,5) 0,004
Peak CRP (mg/dL) 14.3 (6.0-16.2) 7.8 (5.1-11.1) 1,14 (1,06-1,22) <0,0001
SIRS 47.3% 41.8% - 0,6
Post-TAVI aortic failure ≥ +2/4 5.3% 5.4% - 0,99
Major vascular complication 10.5% 4.5% - 0,2
Bleeding Major 26.3% 20.7% - 0,2
Life-threatening 26.3% 4.5% 7,85 (2,62-23,5) <0,001
Blood transfusion 2 to 3 RBC units 15.8% 5.5% 4,3 (1,20-15,5) 0,02
≥ 4 RBC units 26.3% 3.6% 9,4 (3,24-27,2) <0,001
Stage I 52.6% 58.2% 8,2 (3,0-23) <0,001
ARF Stage II 10.5% 1.8% 14,4 (2,9-72) 0,001
Stage III 5.3 0.9 14,7 (1,8-123) 0,013
New pacemaker 42.1% 19.8% 2,72 (1.09-6,8) 0,03
NYHA FC III heart failure at 30 days  38.5%  0.0% 66,8 (16-279) <0,001

HR: hazard ratio; CI: confidence interval; BMI: body mass index; NYHA: New York Heart Association; FC: functional class; CAD: coronary artery disease; PVD: peripheral vascular disease; COPD: chronic obstructive pulmonary disease; STS: Society of Thoracic Surgeons; LVEF: left ventricle ejection fraction; CRP: high sensitive C-reactive protein; SIRS: systemic inflammatory response syndrome; TAVI: transcatheter aortic valve implantation; RBC: red blood cell; ARF: acute renal failure. The Mann-Whitney test (numeric variables) and the chi-square or Fisher exact tests (categorical variables) were used.