Table 2. – Laboratory results among different groups.
| Median (IQR) | ||||
|---|---|---|---|---|
|
| ||||
| Characteristic | Total (n=337) | Normotension (n=225) | Hypertension (n=112) | p-valuea |
| Blood cell count | ||||
| White blood cell count, ×109/L (normal range 3.5-9.5) | 4.81(3.81-6.57) | 4.65(3.63-5.97) | 5.61(4.08-7.82) | .0005 |
| Neutrophil count, ×109/L (normal range 1.6-6.3) | 3.24(2.25-5.02) | 2.96(2.13-4.25) | 3.91(2.89-6.78) | <0.0001 |
| Lymphocyte count, ×109/L (normal range 1.1-3.2) | 0.89(0.63-1.25) | 0.97(0.66-1.33) | 0.76(0.58-1.10) | 0.0011 |
| Monocyte count, ×109/L (normal range 0.1-0.6) | 0.37(0.26-0.50) | 0.36(0.26-0.49) | 0.41(0.26-0.54) | 0.1051 |
| Platelet count, ×109/L (normal range 125-350) | 181(132-232) | 181.5(132.8-227.3) | 180(130-238) | 0.8235 |
| Blood lipids and electrolytes | ||||
| Total cholesterol, mmol/L, (normal range 2.8-5.2) | 3.53(3.01-4.17) | 3.43(2.99-4.13) | 3.70(3.06-4.17) | 0.1034 |
| Triglyceride, mmol/L, (normal range 0.56-1.7) | 0.93(0.69-1.35) | 0.88(0.64-1.31) | 1.01(0.77-1.58) | 0.0127 |
| HDL, mmol/L, (normal range 0.9-2.1) | 1.1(0.92-1.31) | 1.11(0.93-1.31) | 1.09(0.90-1.30) | 0.6562 |
| LDL, mmol/L, (normal range 1-3.35) | 2.02(1.64-2.48) | 1.92(1.63-2.44) | 2.1(1.67-2.61) | 0.0463 |
| sdLDL, mmol/L, (normal range 95-538) | 121(86-184) | 115.0(81-174) | 131(93-194) | 0.0976 |
| Serum | ||||
| Potassium, mmol/L (normal range 3.5-5.3) | 3.71(3.38-4.07) | 3.72(3.43-4.05) | 3.71(3.29-4.17) | 0.7970 |
| Calcium, mmol/L (normal range 2.11-2.52) | 2.16(2.07-2.26) | 2.17(2.09-2.27) | 2.14(2.05-2.24) | 0.0612 |
| Inflammatory biomarkers | ||||
| hsCRP, mg/L (normal range 0-3) | 31.70(9.08-65.52) | 27.2(6.6-61.3) | 44.2(14.55-76.05) | .015 |
| Procalcitonin, ng/mL (normal range 0-0.1) | 0.065(0.04-0.14) | 0.0525(0.04-0.12) | 0.09 (0.05-0.21) | <0.0001 |
| SAA, mg/L (normal range 0-10) | 93.61(32.24-196.1) | 104.7(27.57-223.3) | 86.16(38.77-159.6) | .5855 |
| Cardiac biomarkers | ||||
| TnT, ng/mL (normal range 0-0.014) | 0.009(0.006-0.014) | 0.008(0.005-0.013) | 0.012(0.008-0.0215) | <0.0001 |
| Creatine kinase-MB, ng/mL (normal range 0-6.22) | 1.12(0.68-2.31) | 1.00 (0.66-1.93) | 1.53(0.93-3.05) | 0.0005 |
| Myoglobulin, ng/mL (normal range 7.4-105.7) | 47.20(27.80-86.00) | 40.9(25.90-67.45) | 67.20(30.65-131.7) | 0.0004 |
| NT-proBNP, pg/mL (normal range 0-222) | 198.4(55.38-488.7) | 124.8(47.75-386.6) | 243.8(107.1-809.3) | 0.0021 |
| Blood gas analysis | ||||
| PaO2, mm Hg (normal range 70-107) | 85.0(62.3-118.0 | 93(74-121.5) | 77(56.0-110.0) | 0.0095 |
| PaO2/FiO2, mm Hg | 376.2(229.3-469.0) | 390.5(274.5-504.8) | 293.1(168.3-419.1) | 0.0003 |
| PaCO2, mm Hg (normal range 35-45) | 38(33-44) | 39(34-44) | 36(32-44) | 0.0829 |
| PH (normal range 7.35-7.45) | 7.42(7.40-7.46) | 7.42(7.40-7.45) | 7.43(7.40-7.46) | 0.4852 |
| BE, mmol/L, (normal range -3-3) | 1.3(-0.7-3.0) | 1.4(0-3.1) | 0.6(-1.9-2.8) | 0.0646 |
| Liver and renal function | ||||
| Alanine Aminotransferase, IU/L (normal range 9-50) | 25.0(16.0-38.0) | 23(15.75-34) | 27.0(16.0-47.0) | 0.0252 |
| Aspartate Aminotransferase, IU/L (normal range 15-40) | 28.0(19.0-40.0) | 26(18.0-37.0) | 29(20.0-45.0) | 0.0382 |
| Total Protein, g/L (normal range 65-85) | 63.7(60.2-67.3) | 64.10(60.3-67.3) | 63.5(59.5-67.2) | 0.5332 |
| Albumin, g/L (normal range 40-55) | 36.5(33.0-39.3) | 37.4(34.1-40.1) | 33.7(31.3-38.0) | <0.0001 |
| Globulin, g/L, (normal range 20-40) | 27.0 (25.1-30.4) | 26.5(24.5-29.0) | 28.6(26.2-32.4) | <0.0001 |
| Total bilirubin, μmol/L (normal range 2-23) | 7.8(5.6-11.0) | 7.2(5.3-9.8) | 9.6(6.6-12.5) | 0.0001 |
| Direct bilirubin, μmol/L (normal range 0-8) | 3.0(2.2-4.4) | 2.9(2.1-4.0) | 3.3(2.4-4.9) | 0.0138 |
| Creatinine, μmol/L (normal range 57-97) | 64.0(53.0-75.0) | 62(52.3-73.0) | 68(54.5-85.8) | 0.0144 |
| Urea nitrogen, μmol/L (normal range 3.1-8) | 4.24(3.36-5.80) | 4.13(3.34-5.37) | 4.88(3.51-6.26) | 0.0113 |
IQR: interquartile range; HDL: high-density lipoprotein; LDL: low-density lipoprotein; sdLDL: small dense Low-Density Lipoprotein; hsCRP: high-sensitivity C-reactive protein; TnT: troponin T; NT-proBNP: N-terminal pro–brain natriuretic peptide. a: statistical difference (numerical variable) between normotension and hypertension groups were evaluated by the Mann-Whitney U test.