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. 2021 Jul 7;117(5):911–921. [Article in Portuguese] doi: 10.36660/abc.20200733

Table 4. – The association between ACEI/ARB use and disease severity in COVID-19 patients with hypertension.

    Antihypertensive treatment  

  Total (n=112) ACEI/ARB treatment (n=20) Other hypotensive drug (n=64) No hypotensive treatment (n=28) p-value
Disease severity         0.3487a
Moderate 20(17.8) 3(15) 11(17.2) 6(21.4)  
Severe 69(61.6) 13(65) 36(56.3) 20(71.4)  
Critical 23(19.3) 4(20) 17(26.6) 2(7.1)  
Clinical outcome         1.0000a
Discharge 92(82.1) 16(80) 49(76.6) 27(96.4)  
Death 20(17.9) 4(20) 15(23.4) 1(3.6)  

ACEIs: angiotensin-converting enzyme inhibitors; ARBs: angiotensin II receptor blockers. a: R X C Chi-square test was used to analyze the difference between groups.