Figure 8.

Linkage disequilibrium (LD) between the top five MHC association signals in the European and South Asian models

Association plots for the five most significant psoriasis-associated MHC loci in South Asians (A–E) and Europeans (F–J) are shown in decreasing top to bottom order of their significance in the full regression model. LD (W_n² coefficient) is depicted with line segments connecting pairs of South Asian and European loci; the color of the line indicates the population in which the LD was measured (red, South Asian; blue, European), and the thickness of the line is scaled linearly with the magnitude of LD. Only LD values of W_n² ≥ 0.1 are shown.