Table 1.
Psoriasis loci established by the transethnic meta-analysis
| Locus | Marker | Location (hg19) | RA/NRA | SAS |
EUR |
Transethnic |
||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | Direction | ||||
| 1p36.22 | rs2103876 | 1:12053100 | T/C | 1.19 (1.07–1.31) | 7.96E−04 | 1.10 (1.06–1.14) | 1.30E−07 | 1.11 (1.07–1.14) | 1.18E−09 | ++−+++++++ |
| 1q24.2 | rs12046909 | 1:168507463 | C/T | 1.21 (1.09–1.34) | 3.85E−04 | 1.13 (1.08–1.18) | 5.56E−07 | 1.14 (1.09–1.19) | 1.68E−09 | ++++++++++ |
Abbreviations: Direction, the direction of effect of the risk allele for 10 studies: PsA GWAS, CASP GWAS, Kiel GWAS, Genizon GWAS, WTCCC2 GWAS, Exomechip, PAGE, GAPC, and two South Asian GWASs; EUR, European; NRA, non-risk allele; RA, risk allele; SAS, South Asian.