Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 7;49(22):12644–12660. doi: 10.1093/nar/gkab1166

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 5. — G4 ligand immunofluorescence staining in A549 cells and nucleus visualized with DAPI. Fluorescence wide-field microscopy images of A549 cells (A) untreated, and after 16 h incubation with (B) 5 μM PDC-4,3-BrdU, (C) 5 μM PDC-4,3-Alk control, obtained by treatment with 5-BrdU-N3 in the absence of copper, (D) 5 μM PDC-4,3-Alk copper-based click reaction in the presence of 50 μM 5-BrdU-N3, 100 μM CuSO₄·5H₂O, 500 μM THPTA and 5 mM NaAsc, and (E) magnification Alexa Fluor 488 images. Arrows indicate nuclear foci. Images are represented as a Z-projection; scale bar: 20 μm.