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Detection of G-quadruplexes formed in the human PDGFR-β core promoter using (A and B) DMS footprinting and (C) UV crosslinking. (A) DNA cleavage fragments of PDGFR-β core promoter G-rich region (WT) resolved by denaturing gel electrophoresis. (B) Digitization of the gel in (A). (C) UV crosslinking between SBED-GMP and WT DNA detected by denaturing gel electrophoresis.
