Fig. 5.

(A) Average distance run per mouse per day during the 4 week running wheel exposure. (B) Voluntary running led to a significant increase in the number of doublecortin labeled cells (immature neurons) compared to sedentary mice. (C) Representative low and high magnification doublecortin labeling in sedentary and (D) runner mice. Scale bars in low magnification images = 100 μm and in high magnification panels = 20 μm. Data shown in (A) are mean ± SEM. In (B) the box represents the median and 25th and 75th quartiles and whickers represent the 5th and 95th percentiles.