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. 2021 Oct 7;8(1):88–98. doi: 10.1002/cjp2.241

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© 2021 The Authors. The Journal of Pathology: Clinical Research published by The Pathological Society of Great Britain and Ireland and John Wiley & Sons Ltd. This article has been contributed to by US Government employees and their work is in the public domain in the USA.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Scatter plot representation of median ± range of the percentage positive tissue area for markers measured by IHC and quantified by digital pathology using the HALO image analysis platform. Data were analyzed by unpaired Mann–Whitney test for differences between individual histological types compared. pRCC2 acted as comparison group for all analysis, as it had the largest subject size. pRCC2, papillary renal cell carcinoma type 2 (n = 44) (red); pRCC1, papillary renal cell carcinoma type 1 (n = 20) (green); CDC, collecting duct carcinoma (n = 14) (blue); HGUC, high‐grade urothelial carcinoma (n = 5) (magenta). ****p < 0.0001; ***p < 0.0005; **p < 0.005; *p < 0.05.