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. 2021 Dec 17;48(6):705–720. doi: 10.1134/S1062359021060108

Table 1.

The top 10 literature statistics

Literature Cited
1

Cong L, Ran FA, Cox D, Lin SL, Barretto R, et al.

Multiplex Genome Engineering Using CRISPR/Cas Systems

SCIENCE. 2013 FEB 15; 339 (6121): 819–823

5452
2

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, et al.

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

SCIENCE. 2012 AUG 17; 337 (6096): 816–821

4302
3

Mali P, Yang LH, Esvelt KM, Aach J, Guell M, et al.

RNA-Guided Human Genome Engineering via Cas9

SCIENCE. 2013 FEB 15; 339 (6121): 823–826

3886
4

Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, et al.

Genome engineering using the CRISPR-Cas9 system

NATURE PROTOCOLS. 2013 NOV; 8 (11): 2281–2308

2781
5

Hsu PD, Lander ES, Zhang F

Development and Applications of CRISPR-Cas9 for Genome Engineering

CELL. 2014 JUN 5; 157 (6): 1262–1278

1939
6

Doudna JA, Charpentier E

The new frontier of genome engineering with CRISPR-Cas9

SCIENCE. 2014 NOV 28; 346 (6213): Art. No. 1258096

1770
7

Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, et al.

DNA targeting specificity of RNA-guided Cas9 nucleases

NATURE BIOTECHNOLOGY. 2013 SEP; 31 (9): 827–+

1716
8

Wang HY, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, et al.

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated

Genome Engineering

CELL. 2013 MAY 9; 153 (4): 910–918

1675
9

Gaj T, Gersbach CA, Barbas CF

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

TRENDS IN BIOTECHNOLOGY. 2013 JUL; 31 (7): 397–405

1488
10

Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, et al.

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

CELL. 2013 FEB 28; 152 (5): 1173–1183

1479