Fig. 1. Exploration of PLC architecture with ST.
(A) Workflow of PLC samples collection, processing for ST and WES, and data analysis. (B) UMAP (Uniform Manifold Approximation and Projection) plot of spots from all sections, colored by their sample source, the number of expressed unique molecular identifiers (nUMI) and genes (nGene), respectively. HCC-1N represented the N section of HCC-1. (C) UMAP plot of cell type enrichment scores from all sections. Each dot represents a spot of ST sections, and the shade of color represents the scores of the corresponding cell type.
