Table 1. Baseline Characteristics.
| HFpEF | HFmrEF | P-value | |
|---|---|---|---|
| Age, years | 66.5 (61 - 76) | 68 (64- 77) | 0.5 |
| Sex, male, n (%) | 18 (60) | 23 (76.6) | 0.09 |
| Body mass index, kg/m2 | 32 (27.7 - 36.3) | 29.6 (26.5 - 32.4) | 0.06 |
| NYHA, n (%) | |||
| II | 14 (46.6) | 9 (30) | 0.3 |
| III | 16 (53.4) | 21 (70) | 0.3 |
| Laboratory | |||
| Creatinin, mg/dL | 1.09 (0.89 - 1.25) | 1.07 (0.9 - 1.23) | 0.9 |
| eGFR, mL/min/1.73 m2 | 70 (51.4 - 97.1) | 65.1 (50.5 - 88.4) | 0.5 |
| NT-proBNP, pg/mL | 310 (250 - 372) | 267 (226 - 361) | 0.9 |
| Echocardiographic parameters | |||
| LVEF, % | 57 (55 - 59) | 47 (45 - 48) | 0.0000001 |
| LAVI, mL/m2 | 36.6 (30.1 - 40.8) | 40.1 (34.7 - 46.7) | 0.08 |
| LVEDV, mL | 100 (82 - 114) | 129.5 (98 - 150) | 0.008 |
| LVEDD, mm | 50 (47 - 53) | 54.5 (50 - 58) | 0.002 |
| LVMI, g/m2 | 115 (100 - 131) | 112 (105 - 130) | 0.7 |
| Comorbidity, n (%) | |||
| Coronary artery disease | 19 (63.3) | 23 (76.6) | 0.4 |
| Myocardial infarction | 8 (26.6) | 17 (56.6) | 0.03 |
| Diabetes mellitus | 20 (66.6) | 24 (80) | 0.4 |
| Atrial fibrillation | 8 (26.6) | 15 (50) | 0.1 |
| Treatment, n (%) | |||
| ACEI other than perindopril | 18 (60) | 21 (70) | 0.6 |
| ARB | 12 (40) | 7 (23.3) | 0.2 |
| Diuretics | 5 (16.6) | 11 (36.6) | 0.1 |
HFpEF: heart failure with preserved ejection fraction; HFmrEF: heart failure with mid-range ejection fraction; NYHA: New York Heart Association; eGFR: estimated glomerular filtration rate; NT-proBNP: N-terminal prohormone of brain natriuretic peptide; LVEF: left ventricular ejection fraction; LAVI: left atrial volume index; LVEDV: left ventricular end-diastolic volume; LVEDD: left ventricular end-diastolic diameter; LVMI: left ventricular mass index; ACEI: angiotensin-converting enzyme; ARB: angiotensin II receptor blocker.