Table 2. Echocardiographic Parameters Before and After 12-Month Therapy With Perindopril.
Before perindopril prescription | After 12-month therapy with perindopril | P-value | |
---|---|---|---|
HFpEF | |||
LAVI, mL/m2 | 36.6 (30.1 - 40.8) | 36.2 (30.2 - 41.8) | 0.6 |
LVMI, mL/m2 | 115 (100 - 131) | 114.8 (93.6 - 125.7) | 0.04 |
LVEDD, mm | 50 (47 - 53) | 50 (47 - 52) | 0.1 |
LVEDV, mL | 100 (82 - 114) | 98.5 (82 - 113) | 0.02 |
EF, % | 57 (55 - 59) | 57.5 (56 - 59) | 0.98 |
HFmrEF | |||
LAVI, mL/m2 | 40.1 (34.7 - 46.7) | 38.2 (34.5 - 46.5) | 0.1 |
LVMI, mL/m2 | 112 (105 - 130) | 113.1 (99.9 - 125.6) | 0.008 |
LVEDD, mm | 54.5 (50 - 58) | 53.5 (49 - 57) | 0.004 |
LVEDV, mL | 129.5 (98 - 150) | 121.5 (98 - 150) | 0.001 |
EF, % | 47 (45 - 48) | 48 (46 - 50) | 0.0002 |
HFpEF: heart failure with preserved ejection fraction; HFmrEF: heart failure with mid-range ejection fraction; LAVI: left atrial volume index; LVMI: left ventricular mass index; LVEDD: left ventricular end-diastolic diameter; LVEDV: left ventricular end-diastolic volume; EF: ejection fraction.