Table 2.
Patient characteristics of COVID-19 and viral pneumonia patients.
| COVID-19 | Other viral pneumonia | |
|---|---|---|
| Number of admissions | 6343 | 2256 |
| Median age (IQR) | 65 (57–72) | 67 (58–75) |
| Number of patient with unknown age | 0 | 37 |
| Number of males (%) | 4524 (71.3) | 1123 (49.8) |
| Median BMI (IQR) | 28.1 (25.5–31.7) | 25.5 (22.5–29.7) |
| Number of patient with unknown BMI | 162 | 145 |
| Comorbidities⁎ | ||
| Malignancy | 187 (2.9) | 133 (5.9) |
| Immunological insufficiency | 574 (9) | 359 (15.9) |
| COPD | 614 (9.7) | 1069 (47.4) |
| Chronic respiratory insufficiency | 270 (4.3) | 417 (18.5) |
| Chronic renal failure | 285 (4.5) | 157 (7) |
| Chronic cardiovascular insufficiency | 103 (1.6) | 85 (3.8) |
| Cirrhosis | 22 (0.3) | 10 (0.4) |
| Diabetes | 1506 (23.7) | 451 (20) |
| Vasoactive medication in first 24 h of ICU admission | 3584 (56.5) | 908 (40.2) |
| Mechanical ventilation at ICU admission | 2205 (34.8) | 1201 (53.2) |
| Mechanical ventilation in first 24 h of ICU admission | 4243 (66.9) | 1542 (68.4) |
| Median APACHE III APS (IQR) | 47 (38–59) | 48 (37–61) |
| Median APACHE III score (IQR) | 60 (48–73) | 62 (49–77) |
| Median LOS ICU in days (IQR) | 13 (6–25) | 3.6 (1.7–7.6) |
| Median LOS hospital in days (IQR) | 19 (11–34) | 9 (5–16) |
| Median ICU occupancy rate at ICU admission (IQR) | 150 (120−200) | 120 (100−130) |
| Median ICU occupancy during ICU treatment (IQR) | 160 (130−200) | 120 (100–130) |
| ICU mortality N(%) | 1709 (26.9) | 336 (14.9) |
| Hospital mortality N(%) | 1960 (30.9) | 444 (19.7) |
*Malignancy: Encompasses malignant lymphoma, acute leukaemia, multiple myeloma, metastases which have been diagnosed by clinical examination or confirmed by a pathology report OR if there is Stage IV cancer.
Immunological insufficiency: HIV-positive with clinical complications, long-term immunosuppressive therapy, corticosteroid use, active chemotherapy, radiotherapy in the past year, chemotherapy or radiotherapy for Hodgkin's or non-Hodgkins lymphoma at any time for IC admission OR documented humoral/cellular deficiencies.
COPD: chronic condition in which pulmonary function swiftly deteriorates.
Chronic respiratory insufficiency: Chronic restrictive, obstructive or vascular conditions in the lungs resulting in very severe restriction of mobility (GOLD IV), registered chronic hypoxia, secondary polycythaemia, severe pulmonary hypertension (PAPsys > 40 mmHg) OR respiratory dependence.
Chronic renal failure: evidence of raised serum creatinine > 177 umol/L (2.0 mg/dl) and renal insufficiency in the medical history OR long-term haemodialysis/peritoneal dialysis prior to the current hospital admission.
Chronic cardiovascular insufficiency: Angina or symptoms at rest or during minimal effort (New York Heart Association class IV).
Cirrhosis: positive biopsy and documented portal hypertension, previous periods of high gastrointestinal bleeding as a result of portal hypertension, previous periods of hepatic failure, coma OR encephalopathy.
Diabetes: medication-dependent form of diabetes diagnosed before the current IC admission.