Overall response rates and major response rates in (A) the intention-to-treat population over time (n = 75 for each treatment arm at each timepoint) and (B) by genotypea and prior treatment status. aResponse rates exclude six patients in the ibrutinib-rituximab arm and eight patients in the placebo-rituximab arm who had unknown genotype. NOTE. Values over 100% are due to rounding. CR, complete response; MR, minor response; ORR, overall response rate; PR, partial response; VGPR, very good partial response.