TABLE 3.
Surgery Related Factors and Risk for Anastomotic Leakage
| Anastomotic Leakage (n = 132) | No Anastomotic Leakage (n = 1430) | ||||
| Variable | Missing | Missing | P Value | ||
| Duration of surgery (min) | 186 (32–385) | n = 4 | 153 (29–483) | n = 60 | 0.000 |
| Surgical procedure | 0.189 | ||||
| Subtotal colectomy | 13 (9%) | 127 (91%) | |||
| Left hemicolectomy | 16 (10%) | 152 (90%) | |||
| Right hemicolectomy | 29 (5%) | 497 (95%) | |||
| Low anterior resection | 37 (13%) | 250 (87%) | |||
| Sigmoid resection | 30 (10%) | 273 (90%) | |||
| Transverse colon resection | 1 (4%) | 25 (96%) | |||
| Rectum resection | 4 (6%) | 58 (94%) | |||
| Reversal of Hartmann | 2 (4%) | 48 (96%) | |||
| Surgical approach | n = 1 | n = 15 | 0.007 | ||
| Open | 31 (23%) | 209 (15%) | |||
| Laparoscopy | 90 (69%) | 1132 (80%) | |||
| Laparoscopy with conversion | 10 (8%) | 74 (5%) | 0.223 | ||
| Anastomotic location | 0.009 | ||||
| Colon | 91 (69%) | 1123 (79%) | |||
| Rectum | 41 (31%) | 307 (21%) | |||
| Anastomotic configuration | n = 5 | n = 40 | 0.005 | ||
| End-to-end | 35 (28%) | 276 (20%) | |||
| End-to-side | 11 (7%) | 94 (7%) | |||
| Side-to-end | 37 (30%) | 304 (22%) | |||
| Side-to-side | 44 (35%) | 716 (51%) | |||
| Suture reinforcement | 42 (32%) | n = 2 | 547 (40%) | n = 49 | 0.163 |
| Anastomotic technique | n = 11 | n = 123 | 0.189 | ||
| Hand sewn | 20 (17%) | 272 (21%) | |||
| Stapled | 100 (82%) | 997 (76%) | |||
| Hand sewn and stapled | 1 (1%) | 38 (3%) | |||
| Stoma type | 0.082 | ||||
| Ileostomy | 15 (94%) | 103 (89%) | |||
| Colostomy | 1 (6%) | 13 (11%) | |||
| Goal directed therapy | 29 (22%) | n = 1 | 277 (20%) | n = 40 | 0.307 |
| Urine production in 1 h (mL) | 95 (0–1180) | 97 (0 – 1280) | 0.395 | ||
| Seniority of surgeon | 0.189 | ||||
| Consultant surgeon | 114 (86%) | 1186 (82%) | |||
| Fellow/register | 18 (14%) | 244 (17%) | |||
| Fit to perform | 119 (100%) | n = 13 | 1347 (99%) | n = 81 | 0.844 |
Data are presented as number (%) or as medians (range) for categorical and continuous variables, respectively. n is number of inclusions if due to missing data this deviates from total. Intraoperative events include: hypoxic events, hypertension, hypercarbia, bradycardia, hypotension, embolism, reanimation, more extensive resection than planned, serosa lesions, bladder and ureteral injuries, intraoperative bleeding, splenectomy or bleeding). A P < 0.05 was considered statistically significant.
Bold numbers are statistically significant.