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Summary of binding constants.
| VHH B5 KD [nM] (n) | NDEL1 KD [µM] (n) | LIS1 KD [nM] (n) | |
|---|---|---|---|
| Monomer (M) | 46 (1.4) | 20 (1.4) | 71 (1.2) |
| Oligomer/Fibril (H) | 66 (1.1) | 13 (2.1) | 31 (2.4) |
| Oligomer/Fibril (M) | 70 (1.1) | 14 (2.5) | 31 (2.8) |
Legend: n – cooperativity index, M – MBP fusion construct, H – His6 fusion construct.
