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. 2021 Dec 17;11:24133. doi: 10.1038/s41598-021-01885-0

Table 2.

Description of HBV and HCV LP patients (N = 2290), categorised by ALD/LSLD in 11 Spanish hospitals.

Overall HBV (N = 505) HCV (N = 1785)
n (%) n (%) n (%)
Late presentation to carea
Yes 588 (25.7) 78 (15.4) 510 (28.6)
Advanced liver disease 552 (24.1) 72 (14.3) 480 (26.9)
Missing values 10 (0.4) 2 (0.4) 8 (0.5)
Fibrosis stage
F3 170 (7.4) 17 (3.4) 153 (8.6)
F4 359 (15.7) 48 (9.5) 311 (17.4)
APRI > 1.5 23 (1.0) 7 (1.4) 16 (0.9)
Late-stage liver disease 122 (5.3) 28 (5.5) 94 (5.2)
Hepatocellular carcinoma 55 (2.4) 10 (2.0) 45 (2.5)
Missing values 78 (3.4) 0 (0) 78 (4.3)
Decompensated cirrhosis defining liver complicationsb
Yes 75 (3.3) 19 (3.8) 56 (3.1)
Jaundice 21 (0.9) 9 (1.8) 12 (0.7)
Hepatic encephalopathy 8 (0.3) 0 (0) 8 (0.4)
Ascites 37 (1.6) 11 (2.1) 26 (1.4)
Variceal bleeding 18 (0.8) 3 (0) 15 (0.8)
Missing values 214 (9.3) 133 (26.3) 186 (10.4)

ALD advanced liver disease, APRI aspartate aminotransferase to platelet ratio, F3 stage 3 fibrosis, F4 stage 4 fibrosis, HBV hepatitis B virus, HCV hepatitis C virus, LP late presentation, LSLD late-stage liver disease.

aLate presentation to care includes those with ALD and LSLD, of which, some patients may classify in both categories (i.e. a patient may have fibrosis F4 and a liver complication).

bNumber of patients for each type of liver complication sum to more than the “YES” total because some patients reported more than one liver complication.