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. 2021 Dec 17;11:24206. doi: 10.1038/s41598-021-03624-x

Table 3.

High risk nsSNPs selected by considering ConSurf and PTM predictions.

Protein SNP ID Mutation ConSurf PTM
Conservation scorea Prediction
MYB rs1361650612 G111S 9 e, f Phosphorylation
rs1179275735 N183S 9 e, f Phosphorylation
rs1247579811 P574S 9 e, f Phosphorylation
MYBL1 rs766676175 G122S 9 e, f Phosphorylation
MYBL2 rs1438994955 S178C 9 e, f Phosphorylation

b buried residue, s predicted structural residue (highly conserved and buried), e exposed residue, f predicted functional residue (highly conserved and exposed).

aHighly variable (1), highly conserved (9).