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. 2021 Dec 17;11:24202. doi: 10.1038/s41598-021-03475-6

Table 2.

The association of leisure-time physical activity with cardiovascular disease.

Leisure-time physical activity, MET-hours/week P trend
 < 7.5 7.5 to < 22.5 22.5 to < 37.5  ≥ 37.5
Incident CVD
Cases/person years 1112/23,581 1939/42,539 857/21,780 1796/44,495
 Model 1 Ref. 0.93 (0.87 to 1.00) 0.82 (0.75 to 0.90) 0.84 (0.78 to 0.91)  < 0.001
 Model 2 Ref. 0.93 (0.86 to 1.01) 0.82 (0.75 to 0.91) 0.81 (0.73 to 0.90)  < 0.001
Incident CHD
Cases/person years 876/24,079 1585/43,352 702/22,132 1496/45,211
 Model 1 Ref. 0.98 (0.90 to 1.06) 0.87 (0.79 to 0.96) 0.91 (0.84 to 0.99) 0.010
 Model 2 Ref. 0.97 (0.89 to 1.05) 0.86 (0.77 to 0.96) 0.86 (0.77 to 0.97) 0.006
Incident stroke
Cases/person years 236/25,744 354/46,648 155/23,653 300/48,344
 Model 1 Ref. 0.78 (0.67 to 0.92) 0.69 (0.56 to 0.85) 0.64 (0.54 to 0.76)  < 0.001
 Model 2 Ref. 0.81 (0.68 to 0.97) 0.72 (0.58 to 0.90) 0.65 (0.50 to 0.83) 0.001

∗< 7.5, 7.5–22.5, 22.5–37.5, and ≥ 37.5 MET-hours/week represented < 1, 1–3, 3–5, and ≥ 5 times of the minimum recommended LTPA level, respectively.

Adjusted for age and sex.

Additionally adjusted for education, smoking status, alcohol intake, consumption of food (meat, vegetables, and fruit), hypertension, hyperlipidemia, diabetes, BMI, MET-hours/week, total sedentary time, and family history of CVD.