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. 2021 Dec 17;11:24191. doi: 10.1038/s41598-021-03638-5

Figure 2.

Figure 2

Histopathologic findings in naturally Usutu virus infected birds. (A) The Spleen of a great grey owl (Supplementary Table S1, #1) showed multifocal coagulative necrosis (asterisk) and lymphoid depletion (arrows; scale bar: 50 µm; HE). (B) The Bursa fabricii of a blackbird (Supplementary Table S1, #3) displayed marked subacute lymphocytolysis (asterisks) in follicular centers and additional histiocytic infiltrations (scale bar: 100 µm; HE). (C) The liver of a blackbird (Supplementary Table S1, #4) presented severe coagulation necrosis (asterisk) accompanied by mild infiltration of lymphocytes and hemosiderin-laden macrophages (scale bar: 50 µm; HE). (D) The heart of a blackbird (Supplementary Table S1, #3) exhibited mild to moderate, multifocal, predominantly interstitial, lymphohistiocytic myocarditis (arrows; scale bar: 50 µm; HE). (E) The cerebellum of a blackbird (Supplementary Table S1, #3) revealed mild, multifocal, perivascularly accentuated, lymphohistiocytic infiltrations (arrows; scale bar: 100 µm; HE). (F) The lung of a blackbird (Supplementary Table S1, #9) showed moderate, peribronchial, lymphohistiocytic inflammation (asterisk; scale bar: 50 µm; HE).