TABLE 1.
Baseline characteristics of patients with MTC in SEER database
| Characteristics | Total (%) | Married (%) | Unmarried (%) | p value b |
|---|---|---|---|---|
| Number | N = 1344 (100) | N = 883 (65.7) | N = 461 (34.3) | |
| Sex | ||||
| Female | 816 (60.7) | 484 (54.8) | 332 (72.0) | <0.001 |
| Male | 528 (39.3) | 399 (45.2) | 129 (28.0) | |
| Age a | ||||
| Mean ± SD | 52.9 ± 15.5 | 54.0 ± 14.1 | 50.7 ± 17.9 | <0.001 |
| <52 | 637 (47.4) | 389 (44.1) | 248 (53.4) | |
| ≥52 | 707 (52.6) | 494 (55.9) | 213 (46.6) | |
| Race | ||||
| White | 1129 (84.0) | 766 (86.7) | 363 (78.7) | <0.001 |
| Black | 127 (9.4) | 53 (6.0) | 74 (16.1) | |
| Others | 88 (6.5) | 64 (7.3) | 24 (5.2) | |
| Tumor stage | ||||
| T1 | 581 (43.2) | 365 (41.3) | 216 (46.9) | 0.281 |
| T2 | 347 (25.8) | 234 (26.5) | 113 (24.5) | |
| T3 | 282 (21.0) | 193 (21.9) | 89 (19.3) | |
| T4 | 134 (10.0) | 91 (10.3) | 43 (9.3) | |
| Nodal stage | ||||
| No | 783 (58.3) | 513 (58.1) | 270 (58.6) | 0.877 |
| N1a | 166 (12.4) | 107 (12.1) | 59 (12.8) | |
| N1b | 395 (29.4) | 263 (29.8) | 132 (28.6) | |
| Metastasis | ||||
| M0 | 1233 (91.7) | 819 (92.8) | 414 (89.8) | 0.062 |
| M1 | 111 (8.3) | 64 (7.2) | 47 (10.2) | |
| Surgery | ||||
| No | 51 (3.8) | 20 (2.3) | 31 (6.7) | <0.001 |
| IT/LT | 94 (7.0) | 63 (7.1) | 31 (6.7) | |
| TT | 1199 (89.2) | 800 (90.6) | 399 (86.6) | |
Variables with statistical significance were shown in bold. Abbreviations: IT/LT, isthmectomy/lobectomy; MTC, medullary thyroid cancer; SEER, The Surveillance, Epidemiology, and End Result; TT: total thyroidectomy or near total thyroidectomy.
a
Age was a continuous variable and grouped by cut‐off point using x‐tile software.
b
Categorical variables were assessed by the chi‐squared test and continuous variables were examined by the Mann–Whitney U test.