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. 2021 Nov 7;10(24):9139–9155. doi: 10.1002/cam4.4405

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© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Pooled estimates of the network meta‐analysis according to PD‐L1 expression. (A) Non‐squamous cohort and (B) squamous cohort. Hazard ratios less than 1 and odds ratios more than 1 favor the former treatment. Significant results are in bold. We did not show the analysis for Anti‐angio + Chemo and Chemo. IO + Anti‐angio + Chemo; Immunotherapy + Anti‐angiogenic therapy + Chemotherapy; IO + Chemo; Immunotherapy + Chemotherapy; IO + IO; Immunotherapy + Immunotherapy; IO + IO + Chemo; Immunotherapy + Immunotherapy + Chemotherapy.