Skip to main content
. Author manuscript; available in PMC: 2021 Dec 18.
Published in final edited form as: Am J Med Genet A. 2020 Nov 18;185(9):2690–2718. doi: 10.1002/ajmg.a.61972

TABLE 4.

Associated malformations and disruptions in twins in this series and reports

Subject MCD DWM ZYG IUFD Associated malformations/disruptions
LP97-138 PMG-SUB-PNH DZ + Optic nerve hypoplasia, panhypopituitarism
LP98-090 PMG-SUB-PNH UZ + Congenital cutis aplasia of scalp
LR00-029 PMG-SUB-PNH UZ + Bilateral clubfeet
LR03-380 None (group 3) UZ Amniotic band disruption sequencea
LR07-038a1 PMG MZ Vocal cord paralysisb
LR12-313a2 PMG-SUB-PNH DWM MZ Amyoplasia (three-limb, see text)
LR17-510 PMG MZ Vocal cord paralysisb
LR18-005 PMG MZ Jejunal atresia, leg contractures, clubfeet
LR18-397 PMG-PNH MZ Arthrogryposis multiplex congenitac
Baker 1996 PMG-SUB-PNH MZ + Congenital contractures, not defined
Malinowski DWM + Gastroschisis (limited details provided)
Mochizuki PMG MZ + Multiple intestinal atresias (at 13 sites)
Shue 2012 PMG MZ + Multiple intestinal atresias (at eight sites)
a

Features included unilateral right anopthalmia with surrounding alopecia, cleft lip and soft palate, multiple constriction bands, multiple shortened fingers and toes.

b

We have observed polymicrogyria with vocal cord paralysis in several singletons as well.

c

Oropharynx, hands, and feet most severe, unable to open his mouth.