Table 2.
HCC risk factors according to multivariate analyses using a Fine-Gray regression model and construction of an HCC risk scoring system (training cohort, n = 1,658).
| Variables | aSHR [95% CI] | p value | Coefficient (ln(SHR)) | Score (x3.5) |
|---|---|---|---|---|
| Age (years) | <0.001 | |||
| ≤60 | Ref. | 0 | ||
| 61–65 | 1.92 [1.21–3.06] | 0.006 | 0.6548859 | 2 |
| >65 | 2.96 [2.02–4.32] | <0.001 | 1.084074 | 4 |
| Male sex | 1.86 [1.23–2.79] | 0.003 | 0.6180754 | 2 |
| Platelet count ≤120 103/mm3 | 1.81 [1.25–2.62] | 0.002 | 0.5935341 | 2 |
| GGT>1.5 ULN | 2.16 [1.46–3.20] | <0.001 | 0.7692455 | 3 |
| Bilirubin >12 μmol/L | 1.63 [1.13–2.36] | 0.010 | 0.4897013 | 2 |
| AFP> 5 ng/ml | 2.53 [1.75–3.65] | <0.001 | 0.9268662 | 3 |
AFP, alpha-fetoprotein; GGT, gamma glutamyltransferase; HCC, hepatocellular carcinoma; (a)SHR, (adjusted) subdistribution hazard ratio.