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Exemplary flow cytometry plots after OTR
Mock sample (not electroporated), TCR KO (KO of endogenous α-chain and β-chain), Single KI (Full TCR targeted into TRAC with concomitant β-chain KO) and Dual KI (α-chain targeted into TRAC and the β-chain into TRBC). All samples are pre-gated on living, single CD8+ lymphocytes.
