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. 2021 Mar 17;117(14):2742–2754. doi: 10.1093/cvr/cvab088

Figure 4.

Figure 4

Vessels-on-chips devices are useful tools to study pathological mechanisms occurring within the vessel wall in early and later stages of atherosclerosis. Preliminary research can be performed in easier fabricated straight PDMS channels, whereas for more extensive and complicated research questions, a more elaborate model can be used by producing a 3D lumen in a hydrogel.