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. 2021 Aug 27;3(4):100210. doi: 10.1016/j.ocarto.2021.100210

Table 4.

Odds ratio's for the association between baseline ankle, foot and ankle/foot pain and incident knee pain.

Exposure Univariate Multivariate1 Multivariate2
Ankle Pain N ​= ​540 N ​= ​540 N ​= ​540
No (n ​= ​462, 188) reference reference reference
Yes (n ​= ​78, 60)
4.86 (2.78 to 8.49), 0.001
4.70 (2.65 to 8.33), 0.001
4.13 (2.21 to 7.72), 0.001
Foot Pain
N ​= ​540
N ​= ​540
N ​= ​540
No (n ​= ​370, 149) reference reference reference
Yes (n ​= ​170, 99)
2.07 (1.43 to 2.99), 0.001
1.92 (1.32 to 2.79), 0.001
1.24 (0.81–1.90), 0.32
Ankle and Foot Pain
N ​= ​424
N ​= ​424

No (n ​= ​358, 139) reference reference
Yes (n ​= ​66, 50) 4.92 (2.70 to 8.99), 0.001 4.56 (2.45 to 8.50), 0.001

All results presented as odds ratios with 95% confidence intervals and P-values.

N-values are presented as the number of participants for the given category with the number of incident cases.

Statistically significant results, at the ≥0.05 level, are shown in bold.

Abbreviations: RKOA, radiographic knee osteoarthritis; BMI, body mass index.

1Adjusted for age, sex, BMI, race and Charlson Comorbidity score (dichotomised).

2Adjusted for sex, age, BMI, race, Charlson Comorbidity score (dichotomised) and were mutually adjusted for the other type of joint pain (ankle or foot).