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. 2021 May 27;3(4):100186. doi: 10.1016/j.ocarto.2021.100186

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Top 10 Ingenuity Pathway Analysis (IPA) predicted canonical pathways from differentially expressed microRNAs and their respective predicted mRNA targets in joint tissues for young vs. old, Sham vs. DMM and old vs. DMM joint tissues. Orange line represents the cut-off for statistical relevance at p < 0.05, corresponding to -log (p-value) ≈ 1.3. Abbreviations; destabilization of the medial meniscus (DMM). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)