Table 2.
Values (%) of Emax and pD2 referring to the vasorelaxant effect of acetylcholine (ACH) and sodium nitroprusside (SNP) in rings of the cranial mesenteric artery of elderly animals, of both sexes, chronically treated with inorganic nitrate NaNO3, 10 mM.
| COMBINED GENDERS (n = 16) | FUNCTIONAL ENDOTHELIUM PRESENT (ACH) |
FUNCTIONAL ENDOTHELIUM ABSENT (SNP) |
||
|---|---|---|---|---|
| Emax | pD2 | Emax | pD2 | |
| CONTROL | 80.04 ± 3,69 | 5.38 ± 0.08 | 114.10 ± 3.37 | 6.61 ± 0.12 |
| NITRATE |
96.18 ± 5.96* |
6.98 ± 0.21** |
113.00 ± 2.38 |
6.99 ± 0.15 |
|
GROUPS (n = 8) |
FUNCTIONAL ENDOTHELIUM PRESENT (ACH) |
FUNCTIONAL ENDOTHELIUM ABSENT (SNP) |
||
|
Emax |
pD2 |
Emax |
pD2 |
|
| FEMALE CONTROL | 76.76 ± 6.03 | 5.11 ± 0.09 | 108.85 ± 2.82 | 7.22 ± 0.19 |
| FEMALE NITRATE | 86.26 ± 7,61 | 6.34 ± 0.22* | 115.91 ± 1.88 | 7.11 ± 0.25 |
| MALE CONTROL | 83.33 ± 4,35 | 5.59 ± 0.11 | 119.30 ± 5.75 | 6.10 ± 0.11 |
| MALE NITRATE | 106.10 ± 8.13* | 7.52 ± 0.31** | 110.40 ± 4.06 | 6.89 ± 0.14 |
Values expressed as mean ± SEM. *p<0.05 **p<0.01 Control vs Nitrate.