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. 2021 Dec 18;21:604. doi: 10.1186/s12872-021-02411-w

Table 5.

Subgroup analysis of two kinds of cardioplegia solution according to whether the aortic clamping time more than 120 min

Outcomes Aortic Clamping time
 ≥ 120 min  < 120 min
DN(n = 29) HTK(n = 26) P-value DN(n = 44) HTK(n = 47) P-value
Aortic clamping time [P50(P25,P75), min] 137(125,160) 146.5(131,164) 0.194 78(63,102) 87(68,99) 0.432
Return to spontaneous rhythm [n(%)] 27(93.1) 11(42.3) 0.000 37(84.1) 27(57.4) 0.005
Dop [P50(P25,P75)] 3(0,3.5) 3(1,3) 0.696 2(1,3) 3(0,4) 0.373
Ne [P50(P25,P75)] 3(1.5,4) 2.5(2,3) 0.620 2(1,3) 3(2,4) 0.025
E [P50(P25,P75)] 2(0,2.5) 2(1,3) 0.437 1(0,2) 1(0,3) 0.233
Postoperative low cardiac output [n(%)] 4(13.8) 6(23.1) 0.373 2(4.5) 6(12.8) 0.166
Postoperative arrhythmia [n(%)] 5(17.2) 9(34.6) 0.140 4(9.1) 10(21.3) 0.107
MV time [P50(P25,P75), hour] 16(11.5,27.5) 19(13.5,27) 0.813 15(10,21.5) 19(13,26) 0.065
ICU stay [P50(P25,P75), hour] 39(19.5,70) 43.5(19,75.5) 0.906 21(20,43) 42(22,68) 0.004
Post-hospital stay [P50(P25,P75), day] 10(6.5,11.5) 10(7,12) 0.799 8(7,11) 9(7,11) 0.773
Transfusion: platelet [P50(P25,P75), unit] 0(0,0) 0(0,1) 0.042 0(0,0) 0(0,1) 0.000
Transfusion: erythrocyte [P50(P25,P75), unit] 1.5(0,5.75) 2(0,4) 0.799 0(0,2) 0(0,4) 0.549
Transfusion: plasma [P50(P25,P75), unit] 5.5(3,11.5) 7(4,11.5) 0.261 3.5(0,5) 4.5(3,7) 0.037
Transfusion: cryoprecipitate [P50(P25,P75), unit] 0(0,8) 0(0,17.5) 0.354 0(0,0) 0(0,0) 0.028
Mortality [n(%)] 2(6.9) 3(11.5) 0.550 1(2.2) 3(6.4) 0.339
Post-operative EF [P50(P25,P75),%] 54(44.5,60.5) 51.5(42,62) 0.933 58.5(53,63) 54(45,61) 0.140
Post-operative SV[P50(P25,P75),ml] 67(50,91.5) 65(51.5,82) 0.418 64.5(54,84) 56(40,66) 0.007
Post-operative CO [P50(P25,P75), L/min] 6.8(4.4,7.7) 6(3.9,7.6) 0.522 5.9(4.8,7.0) 4.8(3.6,6.4) 0.002
Post-operative HR [P50(P25,P75),/min] 91(82,97) 87(78,100) 0.899 90.5(75,104) 86(77,98) 0.551
Post-operative FS [P50(P25,P75), %] 28(22.5,32) 27(21.5,32) 0.692 30(27,34) 28(21,33) 0.294

DN del Nido, HTK histidine-tryptophan-ketoglutarate, Dop dopamine, NE norepinephrine, E epinephrine, MV mechanical ventilation, ICU intensive care unit, EF ejection fraction, SV stroke volume, CO cardiac output, HR heart rate, FS fraction shortening