Table 3. Adjusted Hazard Ratios Between Area Deprivation Index, Medicare-Medicaid Dual Eligibility, and Mortalitya.
| Breastb | P value | Prostatec | P value | Lung | P value | CRC | P value | |
|---|---|---|---|---|---|---|---|---|
| Overall mortality | ||||||||
| ADI quintile | ||||||||
| Q1 | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| Q2 | 1.12 (1.04-1.20) | .002 | 1.11 (1.04-1.19) | .002 | 1.08 (1.03-1.14) | .003 | 1.16 (1.09-1.23) | <.001 |
| Q3 | 1.19 (1.12-1.27) | <.001 | 1.28 (1.19-1.36) | <.001 | 1.10 (1.04-1.16) | .001 | 1.18 (1.12-1.26) | <.001 |
| Q4 | 1.31 (1.23-1.40) | <.001 | 1.36 (1.27-1.45) | <.001 | 1.21 (1.15-1.28) | <.001 | 1.23 (1.16-1.31) | <.001 |
| Q5 | 1.34 (1.26-1.43) | <.001 | 1.51 (1.42-1.62) | <.001 | 1.21 (1.14-1.28) | <.001 | 1.24 (1.17-1.32) | <.001 |
| DE | ||||||||
| No | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| Yes | 1.22 (1.15-1.29) | <.001 | 1.29 (1.21-1.38) | <.001 | 1.14 (1.09-1.20) | <.001 | 1.23 (1.17-1.29) | <.001 |
| Cancer-specific mortality | ||||||||
| ADI quintile | ||||||||
| Q1 | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| Q2 | 1.20 (1.04-1.39) | .01 | 1.00 (0.82-1.22) | .98 | 1.05 (0.98-1.12) | .14 | 1.21 (1.09-1.33) | <.001 |
| Q3 | 1.21 (1.05-1.40) | .008 | 1.22 (1.02-1.47) | .03 | 1.07 (1.00-1.14) | .04 | 1.27 (1.15-1.40) | <.001 |
| Q4 | 1.31 (1.23-1.40) | <.001 | 1.36 (1.27-1.45) | <.001 | 1.21 (1.15-1.28) | <.001 | 1.23 (1.16-1.31) | <.001 |
| Q5 | 1.50 (1.30-1.72) | <.001 | 1.38 (1.15-1.66) | <.001 | 1.16 (1.09-1.24) | <.001 | 1.33 (1.21-1.47) | <.001 |
| DE | ||||||||
| No | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| Yes | 1.23 (1.10-1.37) | <.001 | 1.29 (1.07-1.55) | .007 | 1.14 (1.08-1.21) | <.001 | 1.29 (1.19-1.40) | <.001 |
Abbreviations: ADI, Area Deprivation Index; CRC, colorectal cancer; DE, Medicare-Medicaid dual eligibility; NA, not applicable; Q1, quintile 1; Q2, quintile 2; Q3, quintile 3; Q4, quintile 4; Q5, quintile 5.
a
Adjusted for age, sex, race and ethnicity, marital status, stage, Elixhauser comorbidity index, surgery, radiotherapy, and chemotherapy. Area Deprivation Index and DE were mutually adjusted.
b
For breast cancer, hormone receptor status was additionally adjusted.
c
For prostate cancer, androgen deprivation therapy was additionally adjusted.