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. 2021 Oct 26;24:101619. doi: 10.1016/j.pmedr.2021.101619

Table 2.

Adjusteda Odds Ratios (95% CI) of Having Clinical Symptoms by ENDS Device Types and Use Patterns.

ENDS Device Types and Use Patterns N (%) Any EVALI-like symptom§ vs. no EVALI-like symptoms Any symptom* vs. no symptoms
OR (95% CI) OR (95% CI)
Is your current device refillable?
1. Yes, e-liquid pour 863 (60.3) 1.70 (1.13, 2.56) 1.90 (1.32, 2.73)
2. Yes, e-liquid cartridge replacement 410 (28.6) 1.95 (1.27, 2.99) 1.92 (1.30, 2.82)
3. Not refillable (ref) 159 (11.1) 1.00 1.00
What is the typical nicotine content of your e-liquid?
1: Please specify 336 (23.5) 0.99 (0.69, 1.43) 0.89 (0.63, 1.23)
2. It varies 750 (52.4) 1.31 (0.99, 1.74) 1.42 (1.09, 1.86)
3. Don’t know (ref) 346 (24.2) 1.00 1.00
What is the brand/name of e-liquid you typically buy?
1. Specify the brand/name 523 (36.5) 1.15 (0.88, 1.49) 1.18 (0.92, 1.51)
2. I make my own e-liquid 250 (17.5) 1.40 (1.02, 1.91) 2.28 (1.64, 3.18)
3. Don’t know (ref) 659 (46.0) 1.00 1.00
Use flavored e-cigarettes, yes (vs. no) 1250 (87.3) 1.71 (1.18, 2.48) 1.81 (1.30, 2.52)

Abbreviations: ENDS, electronic nicotine delivery systems; EVALI, e-cigarette, or vaping, product use-associated lung injury; OR, odds ratio; CI, confidence interval.

*

Any symptom including dry mouth, cough, nausea, headache, loss of taste/smell, shortness of breath, chest pain, irregular heartbeat, heartburn, high blood pressure, itching/burning skin, rash, bad breath, irritability, leg cramps, runny nose, stuffy nose, sore throat, stomach pain, hoarse voice, and nightmares.

§

Any EVALI-like symptom including nausea, cough, shortness of breath, chest pain, and stomach pain.

Adjusted for age, sex, race/ethnicity, education level, sexual orientation, income level, cigarette smoking status, use of other tobacco products, number of vaping device uses per day, and length using ENDS.