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. 2021 Dec 18;21:1343. doi: 10.1186/s12885-021-09057-z

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Influence of CT on the antitumor efficacy of antitumor drug in a tumor-bearing mouse model. CT26 murine colon cancer cells (1 × 106) were subcutaneously transplanted into male BALB/c mice. From Day 8 post transplantation, mice were orally administered CT (280 mg/kg) or methyl cellulose (the vehicle for CT) once daily for 10 days. The mice received 5-FU (150 mg / kg, i.p.) on day 10 after transplantation. The data is presented as the mean ± SEM of 6 mice. CT26 group vs CT26 + 5-FU and CT26 group vs CT26 + 5FU + CT group: ** < 0.01. CT26 + 5-FU group vs CT26 + 5-FU + CT group: No significant difference. (Dunnet’s multiple composition test)