Table 1.

Information needed for the tab-delimited input files

Information needed from the VCF file	Description	Mandatory VCF column
CHROM:POS	Chromosome number:position	Yes
ID	Identifier	Yes
REF	Reference base	Yes
ALT	Alternative base	Yes
AA	Ancestral allele	No
CADD_PHRED	Phred-scaled Combined Annotation Dependent Depletion (CADD) score	No
AF	Allele frequency (AF) for the alternative base. The AF should be reported for each population	No

This information can be extracted from the VCF file and provided in a tab-delimited format for the software to calculate the FineMAV scores