Table 2.

Linear Regression Models for MMSE Score

	Simple Linear Regression Modela			Multivariable Linear Regression Modelb
Characteristic	Coefficient	95% CI	P Value	Coefficient	95% CI	P Value
Years of education	0.308	0.212 to 0.404	<0.001	0.294	0.195 to 0.393	<0.001
Age	−0.052	−0.099 to 0.005	0.031	−0.053	−0.103 to 0.002	0.041
Sex (male)	−0.693	−1.319 to 0.067	0.030	−0.520	−1.203 to 0.163	0.134
eGFR	0.011	−0.004 to 0.026	0.141	0.019	0.004 to 0.035	0.016
Diabetes mellitus	−0.081	−0.709 to 0.547	0.798	−0.249	−0.939 to 0.440	0.477
Hypertension	0.210	−0.641 to 1.06	0.627	0.657	−0.210 to 1.525	0.137
Dyslipidemia	0.142	−0.486 to 0.771	0.656	0.021	−0.610 to 0.653	0.947
RNFLt	0.020	−0.010 to 0.050	0.185	0.011	−0.039 to 0.062	0.659
GCCt	0.027	−0.014 to 0.067	0.202	0.038	−0.035 to 0.111	0.306
SVP-VD	0.022	−0.049 to 0.093	0.538	−0.073	−0.160 to 0.014	0.100
DVP-VD	0.115	0.025 to 0.205	0.013	0.109	0.007 to 0.212	0.037

CI, confidence interval.

^aApart from years of education, the P values for all other parameters were calculated using a linear regression model after adjustment for years of education. Bold values indicate P < 0.05.

^bThe P values were calculated by multivariate linear regression models by entering all of the following variables: years of education, age, sex, eGFR, diabetes mellitus, hypertension, dyslipidemia, RNFLt, GCCt, SVP-VD, and DVP-VD. Bold values indicate P < 0.05.