Table 3.

Cutoff Values, Sensitivities, and Specificities for Serum IL-17 and Procalcitonin Level, Percentage of CD86 Positive Monocytes, CD16 MFI on CD16 Positive Monocytes and CRP in Early Detection of Early Neonatal Sepsis

Parameter	AUC	Cutoff Point	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
CD86+ monocytes (%)	0.951	>36	90.0	90.0	90.0	90.0
CD16 MFI	0.824	>4.3	93.33	63.33	71.8	90.5
IL-17 (ng/L)	0.913	>145	86.67	90.00	89.7	87.1
Procalcitonin (pg/mL)	0.945	>170	96.67	86.67	87.9	96.3
CRP	0.980	>6	96.67	86.67	87.9	100.0

Abbreviations: MFI, mean fluorescence intensity; IL-17, interleukin 17; CRP, C-reactive protein; AUC, area under curve; PPV, positive predictive value; NPP, negative predictive value.