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. 2021 Dec 14;16:8069–8086. doi: 10.2147/IJN.S329855

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© 2021 Ye et al.

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(A) Schematic of the membrane derived from OMV and cancer cell (CC) fusion and the resulting fused membrane camouflaged HPDA NPs to produce HPDA@ [OMV-CC] NPs. (B) Temperature elevation of HPDA NPs and HPDA@[OMV-CC] NPs (100 μg/mL). (C) CLSM image of NHDF cells, MCF-7 cells, and B16-F10 cells stained with Hoechst 33342 and cultured with DiI-dyed HPDA@[OMV-CC] NPs. Adapted with permission from Wang D, Liu C, You S, et al. Bacterial vesicle-cancer cell hybridmembrane-coated nanoparticles for tumor specific immune activationand photothermal therapy. ACS Appl Mater Interfaces. 2020;12(37):41138–41147. Copyright 2020 American Chemical Society.¹⁰⁸