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. 2021 Aug 14;107(1):e303–e314. doi: 10.1210/clinem/dgab595

Table 2.

Univariate linear mixed-effect models of E2 and FSH with study covariatesa

E2b,c FSHb,c
β (SE) P value β (SE) P value
Age −0.06 (0.007) <0.0001 0.05 (0.005) <0.0001
BMI 0.01 (0.004) 0.002 −0.03 (0.003) <0.0001
Race 0.004 <0.001
 White Ref Ref Ref Ref
 Black −0.001 (0.07) 0.98 −0.15 (0.06) 0.006
 Other −0.22 (0.07) 0.002 0.15 (0.06) 0.013
hsCRPb 0.04 (0.02) 0.021 −0.10 (0.02) <0.0001
Physical activity score 0.009 (0.02) 0.57 0.03 (0.01) 0.030
Alcohol use 0.28
 No Ref Ref Ref Ref
 Yes −0.06 (0.05) 0.28 0.06 (0.04) 0.20
Current smoker
 No Ref Ref Ref Ref
 Yes 0.26 (0.09) 0.014 -0.06 (0.07) 0.41
Any medication use
 No Ref Ref Ref Ref
 Yes 0.02 (0.07) 0.79 −0.06 (0.05) 0.31

Abbreviations: BMI, body mass index; E2, estradiol; FSH, follicle-stimulating hormone.

a Cycle day of blood draw included in models

b Log-Transformed

c For continuous variables, data presented per 1-unit increase.