Table 1.
Demographic and baseline clinical characteristics of women transferring day-3 embryos and at least 1 blastocyst
| All (n = 1579) | D3 embryo transfer only (n = 1300) | At least 1 blastocyst transfered (n = 279) | P-value | |
|---|---|---|---|---|
| Age (years) | 29.00 (27.00, 31.00) | 29.00 (27.00, 31.00) | 29.00 (27.00, 31.00) | 0.70 |
| Menstrual cycle (days) | 30.00 (28.00, 30.00) | 30.00 (28.00, 30.00) | 30.00 (28.00, 30.00) | 0.54 |
| Infertility type | ||||
| Primary | 883 (56) | 719 (55) | 164 (59) | 0.29 |
| Secondary | 696 (44) | 581 (45) | 115 (41) | |
| Ethnic background | ||||
| Han Chinese | 1296 (82) | 1061 (82) | 235 (84) | 0.30 |
| Other | 283 (18) | 239 (18) | 44 (16) | |
| BMI (kg/m2) | 21.33 (19.63, 23.05) | 21.33 (19.72, 23.03) | 21.34 (19.48, 23.05) | 0.83 |
| Waist-to-hip ratio | 0.81 (0.78, 0.85) | 0.82 (0.78, 0.85) | 0.81 (0.78, 0.84) | 0.06 |
| Infertility duration (years) | 3.00 (2.00, 5.00) | 3.00 (2.00, 5.00) | 3.00 (2.00, 5.00) | 0.87 |
| Previous birtha | 46 (733/1579) | 46 (604/1300) | 46 (129/279) | 0.95 |
| Previous conceptiona | 46 (733/1579) | 46 (604/1300) | 46 (129/279) | 0.95 |
| AMH (ng/mL) | 5.69 (3.68, 9.18) | 5.62 (3.64, 9.09) | 5.96 (3.77, 9.37) | 0.45 |
| AFC | 23.00 (16.00, 30.00) | 23.00 (16.00, 30.00) | 23.00 (16.00, 30.00) | 0.99 |
| FSH (mIU/mL) | 5.65 (4.82, 6.57) | 5.65 (4.82, 6.56) | 5.61 (4.81, 6.61) | 0.86 |
| LH (mIU/mL) | 3.67 (2.67, 5.02) | 3.68 (2.66, 5.07) | 3.60 (2.70, 4.84) | 0.55 |
| E2 (pg/mL) | 34.00 (27.00, 44.00) | 34.00 (27.00, 44.00) | 33.00 (26.00, 42.00) | 0.15 |
| Progesterone (ng/mL) | 0.24 (0.18, 0.33) | 0.24 (0.17, 0.33) | 0.24 (0.18, 0.34) | 0.19 |
| Testosterone(ng/mL) | 0.28 (0.23, 0.36) | 0.28 (0.23, 0.36) | 0.29 (0.24, 0.37) | 0.13 |
| Total 25(OH)D (ng/mL) | 19.61 (16.61, 22.90) | 19.66 (16.61, 22.89) | 19.22 (16.58, 23.06) | 0.89 |
| Free 25(OH)D (pg/mL) | 4.72 (4.11, 5.34) | 4.72 (4.12, 5.32) | 4.76 (4.09, 5.36) | 0.80 |
| Systolic blood pressure (mm Hg) | 115.00 (108.00, 122.00) | 115.00 (109.00, 122.00) | 115.00 (108.00, 121.00) | 0.34 |
| Diastolic blood pressure (mm Hg) | 76.00 (70.00, 81.00) | 76.00 (70.00, 82.00) | 75.00 (69.00, 80.00) | 0.02 |
| Blood glucose (mmol/L) | 5.15 (4.93, 5.43) | 5.16 (4.94, 5.43) | 5.14 (4.88, 5.42) | 0.27 |
| Triglyceride (mmol/L) | 0.99 (0.72, 1.42) | 1.00 (0.72, 1.42) | 0.98 (0.71, 1.50) | 0.72 |
| Cholesterol (mmol/L) | 4.26 (3.81, 4.81) | 4.26 (3.80, 4.80) | 4.27 (3.87, 4.87) | 0.80 |
| LDL (mmol/L) | 2.72 (2.29, 3.20) | 2.72 (2.29, 3.22) | 2.69 (2.32, 3.18) | 0.76 |
| HDL (mmol/L) | 1.45 (1.22, 1.70) | 1.45 (1.22, 1.70) | 1.48 (1.24, 1.74) | 0.17 |
| Uric acid (μmol/L) | 282.00 (245.00, 327.00) | 282.00 (245.00, 328.00) | 283.00 (247.00, 327.00) | 0.92 |
Data are given as median (IQR) or n (%) unless otherwise noted. Three women got D3 embryo and D5 blastocyst transfer. 276 women got D5 blastocyst only. These cases were analyzed together as the “at least 1 blastocyst transferred” group (n = 279).
Abbreviations: AFC, antral follicle count; AMH, anti-Müllerian hormone; BMI, body mass index; D3, day 3; D5, day 5; E2, estradiol; FSH, follicle-stimulating hormone; HDL, high-density lipoprotein; IQR, interquartile range; LDL, low-density lipoprotein; LH, luteinizing hormone.
a Data are given as % (n/N).