Table 2.

Correlation of bowel urgency days and abdominal pain at Week 8 with clinical outcomes, HRQOL measures, and biomarker levels.

	Bowel urgency days		Abdominal pain
Measures	n	Spearman correlation [95% CI]	n	Spearman correlation [95% CI]
Full Mayo score	206	0.59 [0.49, 0.68]	206	0.41 [0.28, 0.53]
Mayo rectal bleeding subscore	210	0.40 [0.27, 0.51]	210	0.43 [0.31, 0.54]
Mayo stool frequency subscore	210	0.55 [0.45, 0.65]	210	0.35 [0.21, 0.47]
Mayo physician global assessment subscore	210	0.50 [0.38, 0.60]	210	0.42 [0.29, 0.53]
Mayo endoscopic subscore	222	0.42 [0.30, 0.54]	222	0.20 [0.05, 0.33]
Abdominal pain	189	0.54 [0.43, 0.63]	–	–
Bowel urgency	–	–	189	0.54 [0.43, 0.63]
IBDQ	214	−0.50 [−0.61, −0.38]	214	−0.55 [−0.64, −0.20]
SF-36 PCS	214	−0.41 [−0.53, −0.28]	214	−0.52 [−0.62, −0.41]
SF-36 MCS	214	−0.27 [−0.41, −0.13]	214	−0.31 [−0.44, −0.16]
HS-CRP	231	0.34 [0.21, 0.46]	231	0.32 [0.18, 0.44]
Faecal calprotectin	211	0.41 [0.28, 0.53]	211	0.22 [0.08, 0.36]

Estimates between 0 and 0.3 [−0.3] indicate weak correlation [bold text] and > 0.3 to 0.7 [<−0.3 to − 0.7] indicate moderate correlation [plain text].³² All correlations in the table were statistically significant.

CI, confidence interval; HRQOL, health-related quality of life; HS-CRP, high-sensitivity C-reactive protein; IBDQ, Inflammatory Bowel Disease Questionnaire; MCS, Mental Component Summary; PCS, Physical Component Summary; SF-36, 36-Item Short Form Health Survey.